{"product_id":"same-designs-for-health","title":"SAMe","description":"\u003cp style=\"text-align: justify; margin: 0cm 0cm 12.0pt 0cm;\"\u003e\u003cstrong\u003eSAMe\u003c\/strong\u003e \u003cstrong\u003e(as S-adenosyl-L-methionine) \u003c\/strong\u003eis a naturally occurring metabolite found in the human body and in plant and animal foods. It is the most active of all methyl donors and has been compared to adenosine triphosphate (ATP) in its importance for the body. SAMe is naturally synthesized in humans from the amino acid methionine in the presence of the cofactors vitamin B12 and folate.\u003cmeta charset=\"utf-8\"\u003e\u003c\/p\u003e\n\u003cdiv\u003e\n\u003ca href=\"https:\/\/www.designsforhealth.com\/u\/dralex\/\"\u003e\u003cimg data-mce-fragment=\"1\" alt=\"Designs for Health\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0400\/2273\/files\/DesignsforHealthVirtualDispensary_2_-min_480x480.png?v=1675454200\" style=\"display: block; margin-left: auto; margin-right: auto;\"\u003e\u003c\/a\u003e\u003cbr\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\n\u003ca href=\"https:\/\/www.shop.dralexrinehart.com\/pages\/a-to-z-product-list\"\u003e(\u003c\/a\u003e\u003ca href=\"https:\/\/www.designsforhealth.com\/u\/dralex\/\" aria-describedby=\"a11y-new-window-message\" target=\"_blank\"\u003eClick to browse all DFH products)\u003c\/a\u003e\n\u003c\/div\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cp style=\"text-align: justify; margin: 0cm 0cm 12.0pt 0cm;\"\u003eSAMe is involved in the synthesis of neurotransmitters, the hormone melatonin, phospholipids, and polyamines, which control cellular growth. It is also the source of methyl groups inside the nucleus for DNA methylation, which controls gene expression and the masking of genetic damage.*\u003c\/p\u003e\n\u003cp style=\"text-align: justify; margin: 0cm 0cm 12.0pt 0cm;\"\u003eS-adenosyl-L-methionine (SAMe) is an internally produced compound found in every cell of the human body that is involved in more than 100 biochemical reactions. SAMe is naturally synthesized in humans from the energy molecule adenosine triphosphate (ATP) and the amino acid methionine in the presence of adequate levels of folate and vitamin B12. SAMe is highly concentrated in the liver, adrenal glands, and pineal gland, and it is uniformly distributed throughout the brain.\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: justify; margin: 0cm 0cm 12.0pt 0cm;\"\u003eSAMe is integral to cellular energy metabolism and homeostasis, as it serves as the body’s principal methyl donor, a molecule that is added to another compound (e.g., DNA, protein) to support that compound’s proper function in the body.* This process is called methylation, a continuous cycle that is involved in the synthesis and healthy functioning of neurotransmitters, phospholipids, proteins, hormones, DNA and RNA, polyamines, and glutathione (the body’s master antioxidant).* Proper functioning of these substances are critical for optimal nervous, cardiovascular, and immune system activity, hormone balance, detoxification, genetic expression and modification, and energy production.*\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: justify; margin: 0cm 0cm 12.0pt 0cm;\"\u003eDesigns for Health’s SAMe capsules provide 200 mg of stabilized S-adenosyl-L-methionine (SAMe) per capsule to support biochemical pathways crucial to healthy cellular metabolism that require a steady source of SAMe.* These capsules also provide vitamins B6, B12, and folate, which are nutrient cofactors required for the proper and efficient function of SAMe.\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: justify; margin: 0cm 0cm 12.0pt 0cm;\"\u003eThe natural aging process, dietary deficiency of methionine, folate, vitamins B12 and B6 (i.e., poor protein intake, vegan\/vegetarian diets), inflammatory states, emotional\/physical stressors, and genetic variants all contribute to suboptimal levels of SAMe and, thus, may increase demand for this essential compound.\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cp style=\"text-align: justify; margin: 0cm 0cm 12.0pt 0cm;\"\u003e\u003cstrong\u003eBenefits*\u003c\/strong\u003e\u003cbr data-mce-fragment=\"1\"\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eHelps support brain function and memory\u003c\/li\u003e\n\u003cli\u003eMay encourage a positive mental outlook and balanced mood\u003c\/li\u003e\n\u003cli\u003eSupports healthy liver function\u003c\/li\u003e\n\u003cli\u003eHelps support antioxidant status\u003c\/li\u003e\n\u003cli\u003eMay help reduce oxidative stress\u003c\/li\u003e\n\u003cli\u003eMay help support a healthy inflammatory response\u003c\/li\u003e\n\u003cli\u003eHelps maintain cell membrane integrity and fluidity\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: justify; margin: 0cm 0cm 12.0pt 0cm;\"\u003e\u003cstrong\u003eHighlights\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli style=\"text-align: justify;\"\u003e200 mg of patented, stabilized SAMe per capsule\u003c\/li\u003e\n\u003cli style=\"text-align: justify;\"\u003eUses the methylated forms of folate and vitamin B12 for enhanced bioavailability and methylation support*\u003c\/li\u003e\n\u003cli style=\"text-align: justify;\"\u003eUnique encapsulation technology designed to withstand the acidic environment within the stomach, allowing for intact absorption into the small intestine for superior absorption and bioavailability*\u003c\/li\u003e\n\u003cli style=\"text-align: justify;\"\u003eInnovative encapsulation technology allows for the inclusion of cofactors 5-methyltetrahydrofolate (5-MTHF [folate]) and methylcobalamin (vitamin B12) in clinically relevant doses*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSupplement Facts\u003c\/strong\u003e\u003c\/p\u003e\n\u003cdiv style=\"text-align: center;\"\u003e\u003cimg style=\"float: none;\" alt=\"SAMe Designs for Health\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0400\/2273\/files\/sam030-6-sf-min_480x480.jpg?v=1675695125\"\u003e\u003c\/div\u003e\n\u003cp style=\"text-align: justify; margin: 0cm 0cm 12.0pt 0cm;\"\u003e\u003cstrong\u003eRecommended Use:\u003c\/strong\u003e Take 1 capsule per day, preferably on an empty stomach, or as directed by your health-care practitioner. \u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e-See \u003c\/span\u003e\u003ca title=\"Easy, No Hassle Returns\" href=\"https:\/\/www.shop.dralexrinehart.com\/pages\/return-policy\" target=\"_blank\"\u003eSatisfaction\u003cspan\u003e \u003c\/span\u003ePolicy\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSKU \/ UPC Barcode: 879452003774\u003c\/p\u003e\n\u003cp style=\"text-align: justify; margin: 0cm 0cm 12.0pt 0cm;\"\u003e\u003cspan\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\u003c\/p\u003e","brand":"Designs for Health","offers":[{"title":"90ct","offer_id":40279273570389,"sku":"DH-SAM090","price":124.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0400\/2273\/products\/SAMe_90.png?v=1645544473","url":"https:\/\/www.shop.dralexrinehart.com\/products\/same-designs-for-health","provider":"DrAlexRinehart.com","version":"1.0","type":"link"}